Q.3
In bioinformatics, the term "homology" refers to:
EXPLANATION
Mendelian Genetics, Linkage Estimation, Recombination Frequencies & Three-Point Test Cross Mapping
- Definition of Homology in Computational Biology:
- In bioinformatics and evolutionary genetics, homology strictly means sharing common evolutionary ancestry between genes, proteins, or morphological structures.
- Homology is a qualitative attribute (sequences are either homologous or not homologous; they cannot be '80% homologous').
- Homologous genes are subdivided into:
- Orthologs: Homologs separated by a speciation event (often preserving function).
- Paralogs: Homologs arising from gene duplication events within a genome.
- Conclusion: Homology refers to Evolutionarily related genes or proteins (Option 3).
Correct option: (3) Evolutionarily related genes or proteins
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