Complete the following statement - transgenic animals are those... | Agrigyan

Q.7

Animal Genetics and Breeding- ICAR JRF/SRF 2024 (Q.99)

MCQ (Single Correct) +4 −1

Complete the following statement - transgenic animals are those animals which have

Foreign DNA in some of its cells Foreign DNA in all its cells Correct Foreign DNA and RNA in some of its cells Foreign DNA and RNA in all its cells

Transgenic Animals: A transgenic animal is an organism whose genome has been stably modified by the deliberate introduction of an exogenous gene (transgene) from another species using recombinant DNA technology.
Transmission to All Cells:
Because transgenes are introduced into the germline (at the one-cell zygote stage via pronuclear microinjection, lentiviral transduction, or embryonic stem cell transfer), the foreign DNA integrates into the host chromosomes and is replicated during mitosis.
Consequently, the transgene is present in all somatic and germ cells of the resulting founder animal and can be transmitted stably to offspring in a Mendelian fashion. Animals with foreign DNA in only some cells are chimeras or mosaics, not fully transgenic.

Correct option: (2) Foreign DNA in all its cells

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