Ricin Ribosome-Inactivating Protein (RIP): A potent phytotoxin extracted from the seeds of the castor bean plant (Ricinus communis, Euphorbiaceae).
Mechanism of Action: Composed of an A-chain and B-chain linked by a disulfide bridge. The A-chain is an RNA $N$-glycosidase that depurinates a single conserved adenine (A4324) in the 28S ribosomal RNA of the 60S eukaryotic ribosomal subunit, permanently halting elongation and protein synthesis.
Correct option: (2) Ricin
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2
ICAR JRF Biochemistry 29 Jun 2024Shift 1
MCQ (Single Correct)+4−1
Which of following is NOT true about Genetic Code?
Degenerate: Multiple triplet codons specify the same amino acid (61 sense codons code for 20 standard amino acids).
Non-overlapping: Successive triplets are read independently and sequentially.
Comma-less (Unpunctuated): There are no internal spacer nucleotides or punctuations between adjacent codons. Reading frame is determined strictly by the initiation codon (AUG).
Conclusion: Stating that the genetic code has internal punctuations is NOT true (Option 4).
Correct option: (4) Genetic code has internal punctuations to indicate the particular reading frame
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