In a Chi-square test, the contingency table has 5 rows and 5... | Agrigyan

General Agriculture Genome Assembly Statistical Genomics Molecular Biology and Biotechnology Preliminaries of Bioinformatics Evolutionary Biology Bio-Programming and Computational Biology Protein Structure Prediction Biological Database Management System
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Bioinformatics- ICAR JRF/SRF 2024
MCQ (Single Correct)
In a Chi-square test, the contingency table has 5 rows and 5 columns. What is the number of degrees of freedom?

Bioinformatics Subjects

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Bio-Programming and Computational Biology

2 Topics
Bio-Programming: Object-Oriented Principles (C++/Java), Perl & BioPerl in Bioinformatics Machine Learning in Bioinformatics: Hidden Markov Models (HMM), Neural Networks, SVM & Genetic Algorithms

Biological Database Management System

2 Topics
Database Architecture: Three-Level ANSI-SPARC, Relational/E-R Models, Keys & Normalization (1NF to BCNF) SQL (DDL, DML, DQL Queries, Joins) & Sequence Submission Systems (BankIt, Sequin)

Evolutionary Biology

2 Topics
Molecular Phylogenetics: Tree Terminology, Rooted/Unrooted Trees & Tree Construction (UPGMA, Neighbor-Joining) Maximum Parsimony, Maximum Likelihood, Bayesian Inference & Statistical Evaluation (Bootstrapping, Jackknife)

General Agriculture

5 Topics
Soil Science, Plant Nutrition & Reclamation Crop Genetics, Plant Breeding & IPR Agricultural Meteorology & Climate Science Agronomy, Tillage & Field Crop Production Cell Biology, Plant Physiology & Biochemistry

Genome Assembly

2 Topics
Next-Generation Sequencing (NGS) Platforms, Shotgun Sequencing, Read Quality & Coverage Metrics Genome Assembly Algorithms (De Bruijn Graphs, Overlap-Layout-Consensus) & Assembly Tools (Velvet, ABySS, Celera)

Molecular Biology and Biotechnology

2 Topics
DNA/RNA Architecture, Central Dogma, Prokaryotic/Eukaryotic Gene Regulation & Non-Coding RNAs Recombinant DNA Technology, Genomic/cDNA Libraries, Bio-chips & Gene Silencing (RNAi, CRISPR)

Preliminaries of Bioinformatics

2 Topics
Biological Databases (NCBI, EBI, DDBJ, UniProt, PDB), Accession Formats & Information Retrieval (Entrez, SRS) Sequence Alignment: Pairwise Alignment (Needleman-Wunsch, Smith-Waterman), BLAST, FASTA, PAM/BLOSUM & MSA (ClustalW)

Protein Structure Prediction

2 Topics
Tertiary Structure Modeling (Homology, Threading, Ab Initio), Molecular Docking & CATH/SCOP Classifications Protein Secondary Structure Prediction (Chou-Fasman, GOR, Neural Nets) & RNA Secondary Folding (mfold)

Statistical Genomics

2 Topics
Statistical Distributions, Hypothesis Testing & Quantitative Genetics in Genomics Active Linkage Disequilibrium, Genomic Selection, Genome-Wide Association Studies (GWAS) & Microarray Data Normalization
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