Q.7
Fish Physiology and Biochemistry- ICAR JRF/SRF 2024 (Q.57)
MCQ (Single Correct) +4 −1
Do the hypercapnia-induced decrease of intra- and extra-cellular pH values compensate by the increase in one of the following molecules/ions?
  • Branchial Compensation of Respiratory Acidosis:
  • Environmental hypercapnia (elevated water $CO_2$) causes hydration of $CO_2$ in fish blood, producing carbonic acid and driving down intracellular and extracellular $\text{pH}$ (respiratory acidosis):
$$CO_2 + H_2O \rightleftharpoons H_2CO_3 \rightleftharpoons H^+ + HCO_3^-$$
  • Fishes compensate by actively excreting $H^+$ ions and retaining/accumulating bicarbonate ions ($HCO_3^-$) via branchial gill epithelia exchangers ($Na^+/H^+$ and $Cl^-/HCO_3^-$), elevating plasma bicarbonate to restore systemic blood $\text{pH}$.
  • Correct Option: Option 4 (Bicarbonate concentration).
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