Q.75
Fish Physiology and Biochemistry- ICAR JRF/SRF 2024
MCQ (Single Correct)
Which prime ion transporter influences the absorption of both Na+ and Cl- by both Na#/Cl- and Na+/K+/2Cl-cotransporters?
  • The Master Driving Engine of Ion Transport:
  • In branchial and intestinal epithelial cells, the basolateral $Na^+/K^+$-ATPase (sodium-potassium pump) couples ATP hydrolysis to pump $3\ Na^+$ ions out of the cell in exchange for $2\ K^+$ ions pumped inward.
  • This active transport maintains a low intracellular $Na^+$ concentration and a negative intracellular membrane potential, generating a powerful inward electrochemical $Na^+$ gradient.
  • This gradient provides the essential driving force for secondary active cotransporters:
  • $Na^+/Cl^-$ cotransporter (NCC) in freshwater ion absorption.
  • $Na^+/K^+/2Cl^-$ cotransporter (NKCC1 / NKCC2) in seawater ion secretion and intestinal fluid absorption.
  • nalysis:
  • (Na+/K+-ATPase): Correct.

Correct option: (4) Na+/K+-ATPase

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