6
ICAR JRF Microbiology 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1
Repressor molecules bind to
7
ICAR JRF Microbiology 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1

Read the following statements regarding inhibition of oxidative phosphorylation

(A) . Cyanide binds tightly with cytochromes and prevents their functioning
(B) . The antibiotic antimycin A inhibits electron transport chain (ETC) by competing with coenzyme Q.
(C) . The antibiotic piericidin blocks ETC between cytochrome b and c
(D) . Carbon monoxide binds tightly with cytochromes and prevents their functioning (©). The uncouplers prevent ATP synthesis without affecting ETC itself

Choose the correct answer from the options given below:

8
ICAR JRF Microbiology 29 Jun 2024Shift 1
Match the Following +4 −1
Match List-I with List-II:

Choose the correct answer from the options given below:

List - I सूची - I
Mutagen List-I (Mutagen
List - II सूची - II
Results in List-II (Results in
A Nitrous acid Nitrous acid I Both point mutation and deletion Both point mutation and deletion
B 2-amino purine 2-amino purine II GC → AT GC → AT
C Nitrosoguanidine Nitrosoguanidine III Microinsertion and microdeletion Microinsertion and microdeletion
D EMS EMS IV AT → GC and GC → AT AT → GC and GC → AT
E Ethidium bromide Ethidium bromide V AT → GC and occasionally GC → AT AT → GC and occasionally GC → AT
9
ICAR JRF Microbiology 29 Jun 2024Shift 1
Statement Based +4 −1

Given below are two statements

Statement (I) : Shuttle vectors for eukaryotes must contain a segment of DNA from the centromere in order to be properly distributed at cell division
Statement (II) : DNA sequence of replication origins are dissimilar in different eukaryotes, hence yeast origin does not function in higher eukaryotes

In light of the above statements, choose the most appropriate answer from the options given below.

10
ICAR JRF Microbiology 29 Jun 2024Shift 1
Assertion & Reason +4 −1

Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).

Assertion (A) : Studies of chromosome replication in E. coli have shown that about 40 minutes is the minimum time required for genome replication and that is independent of generation time (~20 minutes under optimal conditions)
Reason (R) : In E. coli cells growing under optimal condition, a new round of DNA replication begins before the last round has been completed, and therefore some genes are present in more than one copy

In light of the above statements, choose the correct answer from the options given below.

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