Q.1
Match List-I with List-II:
Choose the correct answer from the options given below:
|
List - I
सूची - I
Enzyme
List-I (Enzyme
|
List - II
सूची - II
Cofactor / Metal
List-II (Cofactor / Metal
|
||
|---|---|---|---|
| A | Carbonic anhydrase Carbonic anhydrase | I | Mo Mo |
| B | Hexokinase Hexokinase | II | $\text{Zn}^{2+}$ $\text{Zn}^{2+}$ |
| C | Nitrate Reductase Nitrate Reductase | III | $\text{Ni}^{2+}$ $\text{Ni}^{2+}$ |
| D | Urease Urease | IV | $\text{Mg}^{2+}$ $\text{Mg}^{2+}$ |
EXPLANATION
Coenzymes, Isozymes, and Vitamins
- Carbonic anhydrase $\rightarrow$ (II) $\text{Zn}^{2+}$: Contains an essential zinc ion coordinated by three histidine residues that activates water for hydration of $\text{CO}_2$ to $\text{HCO}_3^-$.
- Hexokinase $\rightarrow$ (IV) $\text{Mg}^{2+}$: Requires magnesium ($ ext{Mg}^{2+}$) as a cofactor to chelate the negative charges of ATP, forming the true active substrate $\text{MgATP}^{2-}$.
- Nitrate Reductase $\rightarrow$ (I) Mo: Contains a molybdenum pterin cofactor (Moco) essential for transferring electrons to reduce nitrate ($\text{NO}_3^-$) to nitrite ($\text{NO}_2^-$).
- Urease $\rightarrow$ (III) $\text{Ni}^{2+}$: A nickel-dependent metalloenzyme that hydrolyzes urea into ammonia and carbon dioxide.
Correct option: (4) (A) - (II), (B) - (IV), (C) - (1), (DB) - (Ill)
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