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What is a common cause of hemolytic jaundice in animals?
EXPLANATION
Hepatic Diseases
- Mechanisms of Jaundice (Icterus):
- Hemolytic (Pre-Hepatic) Jaundice: Arises from excessive intravascular or extravascular breakdown of erythrocytes, overwhelming the hepatic capacity for bilirubin conjugation:
- Caused by hemoparasites (Babesia, Anaplasma), isoimmune hemolytic anemia, and Bacterial toxins (e.g., Clostridium perfringens type A alpha-toxin phospholipase C, Leptospira interrogans hemolysins) that directly lyse erythrocyte cell membranes.
- Biliary calculi cause post-hepatic obstructive jaundice; hepatic fibrosis causes hepatic jaundice.
- nalysis:
- (Bacterial toxins): Correct cause of hemolytic icterus.
Correct option: (3) Bacterial toxins
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