10
ICAR JRF Veterinary Biochemistry 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1
Cori cycle is the
  • Cori Cycle (Lactic Acid Cycle): An inter-organ metabolic cooperation between actively contracting skeletal muscle (or erythrocytes) and the liver:
  • In Muscle: Glycogen/glucose breaks down through anaerobic glycolysis, producing lactate, which enters the bloodstream.
  • In Liver: Circulating lactate is taken up and converted via hepatic gluconeogenesis back into glucose (utilizing 6 ATP equivalents).
  • In Blood: Newly synthesized glucose is released into circulation and taken up by muscle to replenish glycogen stores.

Correct option: (1) Transport of lactate from muscles to liver and transport of glucose from liver to muscles

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