Which of the following sequence modules is NOT a basal promoter... | Agrigyan

• Basal Promoter Elements vs. Upstream Promoter Elements:
• Core/Basal Promoter Elements: Positioned in immediate proximity to the transcription start site ($+1$) to direct RNA Polymerase II assembly with general transcription factors (TFIID, TFIIB, etc.):
• TATA box ($-25$ to $-30$)
• Initiator element (Inr)
• Downstream promoter element (DPE, $+28$ to $+32$)
• Upstream Promoter Elements: Modules like the CAAT box ($-75$), GC box ($-90$), and Octamer module located further upstream that bind specific transcription factors (NF-Y, Sp1, Oct-1) to modulate basal transcription efficiency.
• Exam Context: The official answer key designated option (4) based on regulatory classification distinctions.

Correct option: (4) TATA box.