8
ICAR JRF Veterinary Microbiology 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1
What is the term used for irreverible cell injury due to hypoxia and cell membrane damage?
EXPLANATION Cell Death
  • Patterns of Irreversible Cell Death:
  • Oncotic Necrosis (Oncosis):
  • The morphological progression of irreversible cell injury resulting from acute severe ATP depletion (hypoxia, ischemia) and plasma membrane pump failure.
  • Characterized by cellular swelling (oncosis), mitochondrial swelling, plasma membrane rupture, and liberation of intracellular contents triggering severe inflammation.
  • Apoptosis: Programmed, energy-dependent cell shrinkage without membrane lysis or inflammation.
  • nalysis:
  • (Oncotic necrosis): Correct.

Correct option: (2) Oncotic necrosis

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