The only non-living anti-coccidial vaccine... | Veterinary Parasitology | Agrigyan

11

ICAR JRF Veterinary Parasitology 29 Jun 2024Shift 1

MCQ (Single Correct) +4 −1

The only non-living anti-coccidial vaccine marketed by Israel in 2002 is

Nobilis COX ATM ADVENT CoxAbic Correct , ParaCOX

Breakthrough Subunit Vaccine: CoxAbic (developed in Israel by ABIC Biological Laboratories / Phibro Animal Health, launched in 2002) is the world's first non-living subunit anticoccidial vaccine for poultry.
Mechanism of Action: CoxAbic is derived from native, affinity-purified gametocyte surface antigens (APGA, containing 56-kDa and 82-kDa glycoproteins) of Eimeria maxima. Inoculated into breeding hens, it stimulates high-titre protective IgG antibodies transferred via egg yolk to broiler chicks, providing maternal passive immunity against E. maxima, E. tenella, and E. acervulina.
Contrasting Vaccines: Paracox, Nobilis COX ATM, and ADVENT are live or live-attenuated coccidiosis vaccines containing live sporulated oocysts.

Correct option: (3) CoxAbic

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