Insulin-Dependent Glucose Transporter: Insulin specifically promotes the exocytotic translocation and cell-surface expression of GLUT4 (Glucose Transporter Type 4).
Target Tissues: Resides in intracellular tubulovesicular endosomes in skeletal muscle, cardiac muscle, and adipose tissue. Binding of insulin to its tyrosine kinase receptor triggers IRS-1/PI3K/Akt activation, mobilizing GLUT4 vesicles to the plasma membrane to facilitate glucose uptake.
Correct option: (3) GLUT4
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2
ICAR JRF Veterinary Physiology 29 Jun 2024Shift 1
MCQ (Single Correct)+4−1
Which of the following is NOT a natural ligand for receptors in the pancrease ?
Pancreatic Receptor Ligands: Cholecystokinin (CCK), Secretin, and Acetylcholine are natural physiological ligands binding specific acinar cell receptors to stimulate pancreatic enzyme and fluid secretion. Gastrin is not a primary natural regulatory ligand for pancreatic acinar secretion [Option 2].
Correct option: (2) Gastrin
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