The developmental process whereby a generic, unspecialized stem or progenitor cell undergoes selective, coordinated gene expression changes to develop stable morphological and biochemical attributes, adopting a specialized physiological role (e.g., neuron, hepatocyte, cardiomyocyte, erythrocyte).
nalysis:
(adoption of a specialized physiological role by a cell): Correct definition.
Correct option: (4) adoption of a specialized physiological role by a cell
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2
ICAR JRF Veterinary Physiology 29 Jun 2024Shift 1
MCQ (Single Correct)+4−1
Somatic cells can be synchronized to the G1 stage of the cell cycle by treatment with
Lovastatin: An inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase that depletes mevalonate. In cultured somatic cells, mevalonate starvation reversibly blocks cells in the $G_1$ phase of the cell cycle.
(Nocodazole and Colchicine disrupt microtubules, arresting cells in M-phase).
nalysis:
(Lovastatin): Correct chemical for G1 synchronization.
Correct option: (3) Lovastatin.
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