Metabolic Actions of IGF-1: Insulin-like Growth Factor-1 (IGF-1 / Somatomedin C) is the primary endocrine mediator of Growth Hormone actions.
Physiological Effects: It stimulates cellular hypertrophy, skeletal elongation, and tissue remodeling, exerting distinct regulatory control over lipid metabolism and nutrient mobilization [Option 3].
Correct option: (3) Increase lipolysis in adipose tissue
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17
ICAR JRF Veterinary Physiology 29 Jun 2024Shift 1
MCQ (Single Correct)+4−1
The hormones responsible for nutrient partitioning
Homeorhetic Nutrient Partitioning Hormones: Growth Hormone (GH / Somatotropin) and Prolactin (PRL) are the primary homeorhetic hormones orchestrating nutrient partitioning.
Lactation Coordination: During early lactation and rapid skeletal growth, GH and PRL coordinate metabolism to prioritize the partitioning of circulating glucose, amino acids, and fatty acids toward the mammary gland or lean muscle mass at the expense of adipose tissue deposition.
Correct option: (1) GHIPRL
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Free Fatty Acid Mobilization : Dehydroepiandrosterone is INCORRECTLY paired [Option 2]. Free fatty acid mobilization (adipose lipolysis) is stimulated by catecholamines (epinephrine), glucagon, growth hormone, and cortisol; DHEA is an adrenal steroid precursor for androgens/estrogens with negligible lipolytic activity.
Lower Lethal Body Temperature: For most domestic mammals and birds, the lower lethal core body temperature is within the range of $15^\circ\text{C}$ to $20^\circ\text{C}$.
Hypothermic Arrest: Cooling below $20^\circ\text{C}$ abolishes electrical pacemaking in the SA node, induces intractable ventricular fibrillation, and depresses medullary respiratory neurons to cause fatal cardiopulmonary arrest.
Correct option: (3) 15-20 °C
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20
ICAR JRF Veterinary Physiology 29 Jun 2024Shift 1
MCQ (Single Correct)+4−1
Which of the following factor may not affect the set point of body temperature?
Hypothalamic Thermoregulatory Set-Point: Factors that directly alter the hypothalamic set-point temperature include Fever (pyrogens), Hibernation, and Circadian rhythms (sleep/pain).
Feeding Effect: Feeding produces postprandial diet-induced thermogenesis (heat increment of feeding) through digestive and metabolic work, but does NOT alter the central hypothalamic thermostat set-point [Option 4].
Correct option: (4) Feeding
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