Lovastatin: An inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase that depletes mevalonate. In cultured somatic cells, mevalonate starvation reversibly blocks cells in the $G_1$ phase of the cell cycle.
(Nocodazole and Colchicine disrupt microtubules, arresting cells in M-phase).
nalysis:
(Lovastatin): Correct chemical for G1 synchronization.
Correct option: (3) Lovastatin.
Explanation not matching this question?क्या व्याख्या इस प्रश्न से मेल नहीं खा रही?Report
7
ICAR JRF Veterinary Physiology 29 Jun 2024Shift 1
MCQ (Single Correct)+4−1
The main phospholipids in most animal cell membranes are the
Phosphoglycerides (Glycerophospholipids) constitute the overwhelming majority ($\gt 50 - 70\%$) of the total phospholipid content of animal cell membranes.
Consist of a glycerol backbone esterified to two fatty acid chains and a phosphorylated polar alcohol headgroup:
Excitation-Contraction Coupling in Striated Muscle: Depolarization of T-tubules activates dihydropyridine receptors (DHPR), opening ryanodine receptors (RyR1) to release $Ca^{2+}$ from the sarcoplasmic reticulum.
Molecular Trigger: Free cytosolic $Ca^{2+}$ binds to Troponin C (TnC), inducing a conformational shift that pulls tropomyosin out of the myosin-binding groove on F-actin filaments, thereby exposing actin cross-bridge binding sites to allow myosin head binding and power-stroke execution (Option 3).
Report Issue / Suggest Correctionत्रुटि रिपोर्ट / संशोधन सुझाव
No official replies published yet for this questionइस प्रश्न पर अभी कोई आधिकारिक समाधान प्रकाशित नहीं है
Have an objection, typo, or doubt? Submit a report in Tab 1. Our subject experts will audit the question and publish the official resolution here.यदि आपको इस प्रश्न या उत्तर कुंजी में कोई आपत्ति है, तो 'त्रुटि रिपोर्ट' टैब से विवरण भेजें। हमारी विषय विशेषज्ञ टीम समीक्षा कर आधिकारिक समाधान प्रकाशित करेगी।