Bacteria synthesize sequence-specific DNA methyltransferases that add methyl groups ($-CH_3$) to adenine or cytosine bases within their own genomic recognition motifs.
This methylation prevents host restriction endonucleases from binding and cleaving the bacterial chromosome, protecting host genomic DNA from degradation by its own restriction enzymes while degrading unmethylated foreign bacteriophage DNA.
Correct Option: Option 4 (Protect DNA from its own restriction enzymes).
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Q.2
Fish Physiology and Biochemistry- ICAR JRF/SRF 2024 (Q.120)
MCQ (Single Correct)+4−1
In salvage reactions of purine biosynthesis, the enzymes are responsible for the transfer of activated ribose phosphate
moiety of 5-Phosphoribosyl-1-Pyrophosphate (PRPP) to purine to form the corresponding ribonucleotides, are
Preformed free purine bases released during intracellular nucleic acid degradation or diet are recycled into nucleotides rather than synthesized de novo (conserving metabolic ATP).
Both reactions utilize 5-Phosphoribosyl-1-pyrophosphate (PRPP) as the activated ribose-5-phosphate donor:
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