Q.60
Which of the following laxative is formed when lactose is heated at high temperatures?
EXPLANATION
Probiotics Selection & Gastrointestinal Survival: Acid/Bile Tolerance (F1F0-ATPase) & FSSAI Standards
- Lactulose Formation via Thermal Isomerization of Lactose:
- Lobry de Bruyn-Alberda van Ekenstein Transformation:
- Under intense heat treatment (e.g., in in-bottle sterilized or UHT milk), lactose (4-O-$\beta$-D-galactopyranosyl-D-glucose) isomerizes into Lactulose (4-O-$\beta$-D-galactopyranosyl-D-fructose).
- Physiological & Diagnostic Properties:
- Non-digestible disaccharide utilized clinically as an osmotic laxative and hepatic encephalopathy therapeutic, and serves as an official chemical index of severe milk heat treatment.
- Conclusion: Lactulose (Option 2).
Correct option: (2) Lactulose
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