Q.39
Mosaicism is a term used in
- Mosaicism in Transgenic Animals:
- In genetic engineering and fish transgenesis (e.g., microinjection of recombinant growth hormone constructs into fertilized teleost eggs):
- Injected DNA construct rarely integrates prior to the first mitotic cleavage, integrating instead into one of multiple blastomeres during the $2-$, $4-$, or $8-$cell stages.
- The resulting founder ($G_0$) animals consist of a patchwork of genetically distinct cells (some with the transgene, some without), a state known as mosaicism.
- Correct Option: Option 3 (transgenesis).
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