Q.72
The largest proteins in antifreeze glycoprotein contain repetitive units of one of the following three amino acids
- Antifreeze Glycoproteins (AFGPs) in Polar Teleosts:
- Found in Antarctic notothenioids (e.g., Trematomus, Pagothenia) and Arctic cod, AFGPs prevent ice crystal growth in body fluids by non-colligative thermal hysteresis (depressing freezing point without altering melting point).
- Primary Structure:
- AFGPs consist of repetitive tandem tripeptide units:
- Each Threonine residue is covalently $O$-glycosidically linked to the disaccharide $\beta\text{-D-galactosyl-(1}\rightarrow 3)\text{-}\alpha\text{-D-N-acetylgalactosamine}$.
- nalysis:
- (Alanine-alanine-threonine): Correct repeating amino acid sequence.
Correct option: (3) Alanine-alanine-threonine
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