Q.95
Fish Physiology and Biochemistry- ICAR JRF/SRF 2024
MCQ (Single Correct) +4 −1
Which following hormone receptors do not have high structural homology?
  • Receptor Superfamilies:
  • Nuclear Receptor Superfamily:
  • Estrogen Receptors (ER), Glucocorticoid Receptors (GR), and Thyroid Hormone Receptors (TR).
  • All share a conserved tripartite domain structure: N-terminal transactivation domain (AF-1), highly conserved zinc-finger DNA-binding domain (DBD), and C-terminal ligand-binding domain (LBD).
  • Vasopressin / Vasotocin Receptors (V1a, V2):
  • Belong to the Rhodopsin-like G-protein coupled receptor (GPCR) superfamily, characterized by 7 transmembrane $\alpha$-helices.
  • They share zero structural homology with nuclear steroid/thyroid receptors.
  • nalysis:
  • (Vasopressin): Correct.

Correct option: (4) Vasopressin

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