Q.96
What distinguishes a coenzyme from a cofactor
EXPLANATION
Enzyme Kinetics: Michaelis-Menten Parameters (Km, Vmax), Catalytic Mechanisms and Coenzymes vs Cofactors
- Definitions in Enzymology:
- Cofactor: A broad umbrella term for any non-protein chemical component required for an enzyme's catalytic activity:
- Can be inorganic metal ions ($Mg^{2+}, Zn^{2+}, Fe^{2+}, Cu^{2+}, Mn^{2+}$).
- Can be organic molecules.
- Coenzyme: A specific subclass of cofactors consisting of complex organic non-protein molecules (often derived from water-soluble B vitamins, such as $NAD^+, FAD, TPP, CoA, PLP$) that transiently bind to the apoenzyme to transfer chemical groups or electrons.
- nalysis:
- (Coenzymes are organic molecules, while cofactors are usually metal ions or inorganic): Correct.
Correct option: (3) Coenzymes are organic molecules, while cofactors are usually metal ions or inorganic
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