Q.74
Microbiology- ICAR JRF/SRF 2024
MCQ (Single Correct)
A temperate, dsDNA bacteriophage which replicates by transposition is
  • Bacteriophage Mu (Mutator Phage): Bacteriophage Mu is a temperate double-stranded DNA bacteriophage that infects E. coli. It is unique because it replicates entirely by replicative transposition.
  • Mutator Phenotype: During both lysogenic integration and lytic amplification, Mu inserts its $37\text{ kb}$ genome essentially at random positions throughout the host chromosome via transposase (MuA) and accessory protein (MuB), causing high-frequency insertion mutations ($1-3\%$ of host genes inactivated, hence named 'Mu' for mutator).
  • Other Phages:
  • Lambda ($\lambda$): Replicates via bidirectional theta replication followed by rolling circle replication, integrating via site-specific recombination at attB.
  • T7: Virulent linear dsDNA phage replicating by concatemer formation.
  • M13: Filamentous ssDNA phage replicating by rolling circle mechanism without transposition.
  • Conclusion: Phage Mu replicates by transposition (Option 3).

Correct option: (3) Mu

Explanation not matching this question? क्या व्याख्या इस प्रश्न से मेल नहीं खा रही? Report
Want to practice this paper in exam conditions? क्या आप परीक्षा जैसे माहौल में अभ्यास करना चाहते हैं? Test yourself in 5-question batch format with timer and hidden answers. 5-प्रश्नों के बैच फॉर्मैट, टाइमर और छिपे उत्तरों के साथ खुद को परखें।
Start Practice Mode → प्रैक्टिस टेस्ट मोड शुरू करें →

Microbiology Subjects

Browse all chapters by subject

Enzymes, Vitamins and Hormones

1 Topic

Physiology of Flowering and Reproduction

1 Topic
Official PYQ Papers

Previous Year Papers of Microbiology

Practice official shift-wise question papers with answer keys and detailed explanations on the actual exam pattern.

1
Total Available Previous Papers

Choose Exam

Exam Directory

Browse official Previous papers and mock tests

10 Major Agriculture Exams Available