Q.31
Veterinary Anatomy- ICAR JRF/SRF 2024
MCQ (Single Correct) +4 −1
Indicate the FDA-approved drug used for the reversal of xylazine-induced sedation in the horse.
  • Alpha-2 Adrenergic Antagonists in Equine Anesthesia:
  • Xylazine is a potent $\alpha_2$-adrenoceptor agonist used for sedation, muscle relaxation, and analgesia in horses.
  • Tolazoline (Tolazoline hydrochloride): An $\alpha_1$ and $\alpha_2$ adrenergic receptor competitive antagonist that is FDA-approved specifically for the reversal of xylazine-induced sedative and cardiovascular effects in horses.
  • (Atipamezole is FDA-approved primarily for dogs and cats; Yohimbine is used in deer and dogs).
  • nalysis:
  • (Tolazoline): Correct FDA-approved agent for horses.

Correct option: (2) Tolazoline

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