Q.32
In peptic ulcers, antacids do have a primary role in’
- Pharmacodynamics of Antacids:
- Antacids (aluminum hydroxide, magnesium hydroxide, calcium carbonate) are basic compounds that chemically react with gastric hydrochloric acid ($HCl$) to form neutral salts and water.
- By instantly raising intragastric pH above $3.5 - 4.0$, antacids neutralize free acidity and inactivate proteolytic pepsin.
- Their primary and most immediate clinical utility is the prompt relief of ulcer pain within minutes of administration.
- (Definitive ulcer healing and relapse prevention are achieved with H2-receptor antagonists or proton pump inhibitors like omeprazole).
- nalysis:
- (Prompt relief of pain): Correct.
Correct option: (1) Prompt relief of pain
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