Q.68
Somatic cells can be synchronized to the G1 stage of the cell cycle by treatment with
- Chemical Cell Synchronization:
- Lovastatin: An inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase that depletes mevalonate. In cultured somatic cells, mevalonate starvation reversibly blocks cells in the $G_1$ phase of the cell cycle.
- (Nocodazole and Colchicine disrupt microtubules, arresting cells in M-phase).
- nalysis:
- (Lovastatin): Correct chemical for G1 synchronization.
Correct option: (3) Lovastatin.
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