Q.70
Which of the following statements are true for lymphoid leukosis?
(A). Itis also called as big liver disease
(B). Itis caused by oncoviruses which are transmitted vertically
(C). The virus is cell associated and it causes neoplastic transformation of T lymphocytes
(D). The disease is seen in adult birds.
Choose the correct answer from the options given below:
- Lymphoid Leukosis in Domestic Poultry:
- Commonly referred to as "Big liver disease" due to massive diffuse nodular enlargement of the liver (hepatomegaly) and spleen. True.
- Caused by exogenous Avian Leukosis Viruses (ALV, family Retroviridae), transmitted both vertically through the egg albumen/yolk and horizontally. True.
- Neoplastic transformation specifically targets B lymphocytes originating in the bursa of Fabricius. (In contrast, Marek's disease transforms T lymphocytes!). Statement C is False.
- The disease has a long incubation period, manifesting clinically in sexually mature adult birds ($\gt 16-24\text{ weeks}$ of age). True.
- nalysis:
- Statements (A), (B), and (D) are correct. Hence, Option 2 is correct.
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