Q.80
Which among the followings is true for sub-clinical form of infectious bursal disease (IBD)?
- Sub-Clinical Form of Infectious Bursal Disease (IBD):
- Age Window: The sub-clinical form occurs when susceptible chicks are infected early in life (below 3 weeks of age), typically during the first 1–2 weeks when maternally derived antibodies decline below protective thresholds.
- Pathological Hallmark: Characterized by massive cytolytic destruction of proliferating immature IgM+ B lymphocytes within the medullary follicles of the bursa of Fabricius, leading to severe, irreversible bursal atrophy and permanent, profound humoral immunosuppression without the acute inflammatory spike, spiking fever, or high mortality seen in birds infected after 3 weeks of age.
- Economic Impact: Results in poor vaccine responses, stunted growth, and devastating secondary bacterial infections (E. coli, gangrenous dermatitis).
Correct option: (3) It is characterized by destruction of immature B lymphocytes and atrophy of bursa.
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