Q.97
Veterinary Pharmacology and Toxicology- ICAR JRF/SRF 2024
MCQ (Single Correct)

Which of the following is not true of the blood-brain barrier:

  • Physiological Properties of the Blood-Brain Barrier (BBB):
  • The BBB is constituted by continuous, non-fenestrated capillary endothelial cells joined by complex tight junctions (zonula occludens), enveloped by a thick basal lamina and astrocyte end-feet (perivascular glial endfeet).
  • Regulatory Direction: The BBB primarily restricts and regulates the influx of substances from the systemic circulation (blood) into the brain extracellular fluid, NOT the passage of substances from brain into blood [Statement 4 is incorrect/FALSE]. (Efflux transporters like P-glycoprotein pump drugs out of endothelial cells back into the capillary lumen).

Correct option: (4) It regulates passage of substances from brain into blood

Explanation not matching this question? क्या व्याख्या इस प्रश्न से मेल नहीं खा रही? Report
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