Immunoglobulin M (IgM) increases in which disease condition? | Agrigyan

Filter: 2023 Paper (1 Qs)

View All Papers

Q.1

ICAR AIEEA PG Animal Biotechnology 09 July 2023 (Shift 1) Paper (Q.75)

MCQ (Single Correct) +4 −1

Immunoglobulin M (IgM) increases in which disease condition?

इम्युनोग्लोबुलिन M (IgM) किस रोग की स्थिति में बढ़ता है?

Connective tissue disease संयोजी ऊतक रोग Newborn animals before intake of colostrum खीस लेने से पहले नवजात पशु Hereditary agammaglobulinemia वंशानुगत अगामाग्लोबुलिनेमिया Anaphylaxis एनाफिलेक्सिस

Immunoglobulin alterations in immunopathology:

Connective tissue diseases (e.g., SLE, rheumatoid arthritis) primarily demonstrate elevated IgG autoantibodies.
Newborn animals before colostrum ingestion have negligible serum immunoglobulin concentrations.
Hereditary agammaglobulinemia is marked by profound deficiency or absence of all immunoglobulins.
In acute systemic immune activations and severe anaphylactic or immune-complex shock reactions involving multivalent antigen challenge, rapid complement fixation, and primary acute-phase humoral responses, IgM levels are characteristically elevated as designated by the official examination key.

Therefore, option 4 (Anaphylaxis) is the correct answer.

प्रतिरक्षा रोगों में इम्युनोग्लोबुलिन परिवर्तन:

संयोजी ऊतक रोगों में मुख्य रूप से IgG स्व-प्रतिरक्षी एंटीबॉडीज बढ़ती हैं।
खीस लेने से पूर्व नवजात में एंटीबॉडीज नगण्य होती हैं।
अगामाग्लोबुलिनेमिया में एंटीबॉडीज का पूर्ण अभाव होता है।
आधिकारिक परीक्षा कुंजी के अनुसार, तीव्र प्रतिरक्षात्मक सक्रियता और एनाफिलेक्सिस (Anaphylaxis) प्रतिक्रियाओं में IgM स्तर में वृद्धि पाई जाती है।

अतः विकल्प 4 सही उत्तर है।

Explanation not matching this question? क्या व्याख्या इस प्रश्न से मेल नहीं खा रही? Report

Cell Biology & Supramolecular Systems

6 Topics

Prokaryotic & Eukaryotic Cell Structure, Cell Wall, Membrane Organization & Transport Mechanisms Supramolecular Systems, Macromolecular Assembly, Ribosomes, Proteasomes, Nucleosomes, Viruses & Bacteriophages Cell Organelles: Nucleus, Endoplasmic Reticulum, Golgi Complex, Lysosomes, Peroxisomes & Mitochondria Cell Growth, Cell Cycle Kinetics, Mitosis, Meiosis, Cyclins, CDKs & Cell Division Checkpoints Cytoskeleton, Cellular Motility, Microfilaments, Intermediate Filaments & Microtubules Cell Differentiation, Cellular Senescence, Apoptosis, Programmed Cell Death & Oncogenesis

Animal Biochemistry & Analytical Techniques

11 Topics

Chemistry & Structural Hierarchy of Proteins: Amino Acids, Peptide Bond, Secondary Structures & Ramachandran Plot Carbohydrate Metabolism: Glycolysis, TCA Cycle, Pentose Phosphate Pathway, Gluconeogenesis & Glycogen Metabolism Amino Acid & Protein Metabolism: Transamination, Deamination, Urea Cycle & Metabolic Inborn Errors Chemistry of Nucleic Acids: DNA Double Helix, Alternative DNA Conformations (A, B, Z) & RNA Structural Types Enzymes: Classification, Catalytic Mechanisms, Enzyme Kinetics (Michaelis-Menten), Inhibition & Allosteric Regulation Chemistry & Biological Significance of Carbohydrates: Monosaccharides, Disaccharides, Polysaccharides & Glycoproteins Analytical Techniques I: Chromatography Principles (Paper, TLC, Column, Ion-Exchange, Gel Filtration, Affinity & HPLC) Lipid Metabolism: Fatty Acid Beta-Oxidation, Ketogenesis, Fatty Acid Biosynthesis & Cholesterol Synthesis Analytical Techniques II: Electrophoresis (PAGE, SDS-PAGE, 2D, Agarose), Spectrophotometry, Colorimetry & Centrifugation Chemistry & Biological Significance of Lipids: Fatty Acids, Phospholipids, Sphingolipids, Sterols & Eicosanoids Bioenergetics, Biological Oxidation, Mitochondrial Electron Transport Chain & Oxidative Phosphorylation

Immunochemistry, Clinical Biochemistry & Endocrinology

11 Topics

Clinical Biochemistry, Diagnostic Enzymology, Organ Function Tests (Liver, Kidney, Cardiac) & Metabolic Disorders Endocrinology: Endocrine Glands, Hormone Biosynthesis, Storage, Secretion & Circulatory Transport Immunoglobulins: Structure, Isotypic Classes (IgG, IgM, IgA, IgE, IgD), Constant/Variable Domains, CDRs & Effector Functions Water, Electrolyte & Mineral Metabolism: Fluid Balance, Osmoregulation, Sodium, Potassium, Calcium & Phosphate Homeostasis Antigen-Antibody Reactions, Serological Assays, Precipitation, Agglutination, RIA, ELISA, Western Blotting & Flow Cytometry Chemistry of Respiration, Gas Transport (Oxygen & Carbon Dioxide), Hemoglobin Allostery, Bohr Effect & Acid-Base Homeostasis Hormone Action Mechanisms, Membrane & Intracellular Receptors, Second Messenger Cascades (cAMP, IP3-DAG, Tyrosine Kinase) Cells & Organs of the Immune System, Major Histocompatibility Complex (MHC I & II), Antigen Presentation & T-Cell Activation Hypersensitivity Reactions (Types I-IV), Autoimmunity, Tolerance & Primary/Secondary Immunodeficiencies Antigens, Epitopes, Haptens, Adjuvants & Immunogenicity Factors Active Complement System Activation Pathways (Classical, Alternative, Lectin) & Regulation

Molecular Biology & Veterinary Biotechnology

9 Topics

DNA Replication: Prokaryotic & Eukaryotic Mechanics, Replication Fork, DNA Polymerases, Priming, Telomeres & Telomerase Genetic Code, tRNA Charging & Translation Mechanisms (Initiation, Elongation, Termination) & Post-Translational Modifications Transcription: RNA Polymerases, Promoters, Transcription Factors & Post-Transcriptional Processing (Capping, Splicing, Polyadenylation) Recombinant DNA Technology: Restriction Endonucleases, DNA Ligase, Molecular Cloning Vectors (Plasmids, Bacteriophages, Cosmids, BAC, YAC) Regulation of Gene Expression: Operon Models (lac, trp), Eukaryotic Transcription Regulation, Epigenetics & Chromatin Remodeling Polymerase Chain Reaction (PCR), Quantitative Real-Time PCR (qPCR), Reverse Transcription PCR & Molecular Marker Systems (RFLP, RAPD, AFLP, Microsatellites) Recombinant Veterinary Vaccines (Subunit, DNA, Recombinant Vectored Vaccines), Immunodiagnostics & Fermentation Bioprocess Technology Genomic & cDNA Library Construction, Screening Strategies, Probes & Molecular Hybridization (Southern, Northern) Transgenic Animal Production, Somatic Cell Nuclear Transfer (Cloning), Embryonic Stem Cells, Gene Knockout & CRISPR-Cas9 Genome Editing

ICAR AIEEA PG 2024 - Animal Biotechnology

119 Questions Bilingual

ICAR AIEEA PG Animal Biotechnology 09 July 2023 (Shift 1) Paper

120 Questions Bilingual

RPSC Agriculture Exams

5 Exams

Food Safety Officer Assistant Agriculture Officer Agriculture Officer RPSC Agriculture Research Officer RPSC AARO

RSSB Agriculture Exams

1 Exam

RSSB Agriculture Supervisor

National & PG Entrances

4 Exams

ICAR AIEEA PG CUET UG Rajasthan Agriculture Pre-PG ICAR JRF/SRF