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ICAR JRF Computer Application 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1
What is a common application of bioinformatics in personalized medicine?
  • Personalized Medicine and Bioinformatics:
  • Personalized (precision) medicine tailors disease prevention and healthcare interventions to an individual's unique genetic profile and molecular phenotype.
  • Genome-Wide Association Studies (GWAS) scan whole genomes across patient cohorts to discover single-nucleotide polymorphisms (SNPs) and genetic variants associated with disease susceptibility, prognosis, and pharmacogenomic drug responses.
  • Bioinformatics tools interpret GWAS loci to predict patient-specific drug efficacy and adverse drug reactions (ADRs).
  • Wet-lab techniques like protein crystallization, virus isolation, and mRNA isolation are physical bench methods, not computational genomics applications.
  • Conclusion: Genome-wide association studies (Option 1).

Correct option: (1) Genome-wide association studies

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