93
Fish Biotechnology- ICAR JRF/SRF 2024
MCQ (Single Correct)
+4
−1
Formation of Holliday junction is key feature of
- Homologous Recombination Model:
- Proposed by Robin Holliday in 1964:
- Homologous recombination (meiotic crossing-over and double-strand break repair) proceeds through the invasion of a single strand into an intact homologous duplex, creating a cross-strand four-way DNA intermediate termed the Holliday junction.
- Branch migration extends the heteroduplex region, followed by resolution of the Holliday junction by junction-resolving endonucleases (resolvases like RuvC in E. coli or GEN1 in eukaryotes) in either horizontal or vertical planes, yielding crossover or non-crossover recombinants.
- nalysis:
- (Homologous recombination): Correct.
Correct option: (4) Homologous recombination
Explanation not matching this question?
क्या व्याख्या इस प्रश्न से मेल नहीं खा रही?
Report Mismatch
त्रुटि बताएं