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ICAR JRF Fish Genetics And Breeding 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1
Which of the following evolutionary models assigns different rates for transitions and transversions?
  • Nucleotide Substitution Models in Molecular Evolution:
  • Jukes-Cantor (JC69) Model: Assumes equal base frequencies and a single uniform substitution rate for all transitions and transversions.
  • Kimura 2-Parameter (K2P / K80) Model: Distinguishes between:
  • Transitions ($A \leftrightarrow G, C \leftrightarrow T$, purine-to-purine or pyrimidine-to-pyrimidine), occurring at rate $\alpha$.
  • Transversions ($A, G \leftrightarrow C, T$), occurring at rate $\beta$.
    • It assigns a higher rate to transitions than transversions (transition bias), which is the standard model in DNA barcoding (COI) of fishes.

  • nalysis:
  • (Kimura-2 Parameter model): Correct.
Correct option: (1) Kimura-2 Parameter model

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