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Interferons are cellular proteins produced mainly in response to
EXPLANATION
National & Global Aquaculture Selection Progr
- Interferons in Antiviral Immunity:
- Interferons (IFNs): A family of inducible cytokine glycoproteins secreted by host somatic cells (including teleost leukocytes) primarily in response to viral infection.
- Secreted IFNs bind to neighboring cell surface receptors, activating the JAK-STAT signaling pathway to induce Interferon-Stimulated Genes (ISGs like Mx protein, PKR), which inhibit viral replication and protein translation.
- Correct Option: Option 1 (Virus infection).
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