79
Fish Genetics and Breeding- ICAR JRF/SRF 2024
MCQ (Single Correct)
+4
−1
The thickness of the chromatin filament is.
EXPLANATION
Chromosomal Cytogenetics: Karyotyping, Banding Techniques (Q/C/G-Banding), FISH and Chromatin Ultrastructure
- Hierarchy of Chromatin Compaction:
- 10 nm Fiber (Beads-on-a-string): Primary packaging consisting of DNA wrapped around octameric histone cores ($H2A, H2B, H3, H4$), forming nucleosomes with a diameter of $\approx 10-11\text{ nm}$.
- 30 nm Fiber (Chromatin filament / Solenoid): The 10 nm nucleosomal filament is coiled into a helical secondary chromatin filament of $30\text{ nm}$ thickness, stabilized by linker histone $H1$.
- 300 nm Loops: Looped domains attached to nuclear scaffold.
- 700 nm Condensed Chromatid: Metaphase chromosome chromatid arm.
- nalysis:
- (30nm): Correct thickness of the chromatin filament (solenoid fiber).
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