Q.1
Veterinary Biochemistry- ICAR JRF/SRF 2024 (Q.120)
MCQ (Single Correct) +4 −1

Identify reactive nitrogen species

(A) .Superoxide
(B) .NO
(C) .Hydroxyl Radical
(D) Peroxynitrite

Choose the correct answer from the options given below:

  • Reactive Nitrogen Species (RNS): Nitrogen-containing free radicals and reactive molecules:
  • Nitric Oxide ($\cdot\text{NO}$): A free radical synthesized from L-arginine by nitric oxide synthases (NOS).
  • Peroxynitrite ($\text{ONOO}^-$): A highly reactive and damaging oxidant formed by the diffusion-controlled reaction of nitric oxide with superoxide:
$$\cdot\text{NO} + \text{O}_2^{\bullet -} \to \text{ONOO}^-$$
  • Reactive Oxygen Species (ROS):
  • Superoxide ($\text{O}_2^{\bullet -}$) and (C) Hydroxyl Radical ($\cdot\text{OH}$) are primary reactive oxygen species (ROS) containing oxygen without nitrogen.
  • Conclusion: Therefore, (B) and (D) only are reactive nitrogen species.

Correct option: (4) (B), (D) only.

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