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Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
A: Under aerobic conditions, TCA cycle is the primary source of energy. R: TCA cycle is followed by electron flow through the respiratory chain generates more ATPs.In light of the above statements, choose the most appropriate answer from the options given below
EXPLANATION
Tricarboxylic Acid Cycle, Amphibolic Nature
- Aerobic Energy Generation:
- Assertion (A): Under aerobic conditions, the tricarboxylic acid (TCA) cycle coupled with the electron transport chain represents the cell's primary catabolic generator of metabolic ATP. (True).
- Reason (R): For each turn of the TCA cycle, oxidation of acetyl-CoA reduces 3 molecules of $NAD^+$ to $NADH$ and 1 molecule of $FAD$ to $FADH_2$. The transfer of electrons from these reduced cofactors through the mitochondrial electron transport chain drives oxidative phosphorylation, producing approximately 10 high-energy ATP equivalents per acetyl-CoA. (True).
- nalysis:
- Both (A) and (R) are correct, and (R) is the correct explanation of (A). Hence, Option 1 is correct.
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