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Which one of the following is the surface acting sulphonamide
EXPLANATION
Sulfonamides & Trimethoprim
- Surface-Acting / Topical Sulfonamides: Sulphacetamide (Sodium sulfacetamide) is a uniquely neutral, highly water-soluble sulfonamide derivative used specifically for topical ophthalmic and dermatological applications.
- Pharmacological Specifics: Its sodium salt dissolves freely at neutral physiological pH (pH 7.4) without causing corneal stinging, conjunctival irritation, or tissue precipitation, penetrating ocular tissues efficiently to treat conjunctivitis and trachoma.
- Systemic Sulfonamides: Sulphadiazine, sulphamethoxazole, and sulphadimidine (sulfamethazine) are orally/parenterally absorbed systemic sulfonamides.
Correct option: (4) Sulphacetamide
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