Macrolides, Lincosamides & Streptogramins: Ribosomal Subunit 50S Peptidyl-tRNA Dissociation - Veterinary Pharmacology & Toxicology | Agrigyan

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Veterinary Pharmacology and Toxicology- ICAR JRF/SRF 2024 (Q.118)
Statement Based +4 −1

Given below are two statements

Statement (I) : Macrolides inhibit protein synthesis by binding the 30S ribosomal subunit at the 23S rRNA site of prokaryote organisms.
Statement (II) : Macrolides dissociate peptidyl-tRNA from the ribosomes during the elongation phase, which disrupts the addition of new peptide bonds and thus prevents the synthesis of new proteins.

In light of the above statements, choose the most appropriate answer from the options given below.

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