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ICAR JRF Veterinary Physiology 29 Jun 2024Shift 1
MCQ (Single Correct) +4 −1
Blood clotting factor XIll is also known as.
  • Nomenclature of Coagulation Factor XIII: Blood coagulation Factor XIII is biochemically designated Fibrin Stabilizing Factor (FSF / Laki-Lorand Factor).
  • Enzymatic Function: Activated by thrombin in the presence of $Ca^{2+}$ ($Factor XIIIa$), it functions as a plasma transglutaminase that catalyzes the formation of covalent $\epsilon-(\gamma-\text{glutamyl})\text{lysine}$ isopeptide cross-links between adjacent fibrin monomers, converting a loose, soluble fibrin polymer into an insoluble, mechanically stable clot.

Correct option: (1) Fibrin stabilizing factor

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