1
Insulin promotes expression of
EXPLANATION
Hormone Classes, Receptors, Second Messengers
- Insulin-Dependent Glucose Transporter: Insulin specifically promotes the exocytotic translocation and cell-surface expression of GLUT4 (Glucose Transporter Type 4).
- Target Tissues: Resides in intracellular tubulovesicular endosomes in skeletal muscle, cardiac muscle, and adipose tissue. Binding of insulin to its tyrosine kinase receptor triggers IRS-1/PI3K/Akt activation, mobilizing GLUT4 vesicles to the plasma membrane to facilitate glucose uptake.
Correct option: (3) GLUT4
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