Skin: 7-dehydrocholesterol is converted by solar UV light into cholecalciferol (Vitamin $D_3$).
Liver: Cholecalciferol undergoes 25-hydroxylation by hepatic 25-hydroxylase to form 25-hydroxyvitamin $D_3$ [calcidiol, $25(OH)D_3$].
Kidney: Calcidiol is transported to the proximal convoluted tubules of the Kidney, where the mitochondrial enzyme $1\alpha$-hydroxylase (stimulated by parathyroid hormone) adds a second hydroxyl group to produce 1,25-dihydroxyvitamin $D_3$ [Calcitriol, $1,25(OH)_2D_3$].
Calcitriol is the biologically active hormonal form released by the kidney into the systemic circulation to regulate calcium and phosphate homeostasis.
nalysis:
(Kidney): Correct organ releasing active calcitriol.
Correct option: (4) Kidney
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Q.32
Veterinary Biochemistry- ICAR JRF/SRF 2024
Arranging Order+4−1
What is the correct sequence of ejaculatory volume
Reflex / Induced Ovulators: Ovulation does not occur spontaneously at the end of the follicular phase; mechanical coital stimulation of vaginal/cervical sensory mechanoreceptors is strictly required to trigger a neuroendocrine surge of GnRH and LH.
Upper Critical Temperature (UCT) is the ambient environmental temperature above which an animal must actively expend metabolic energy (sweating, panting) to dissipate heat and prevent lethal hyperthermia.
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