Veterinary Microbiology- ICAR JRF/SRF 2024

• Therapeutics of Cestode (Tapeworm) Infections:
• Praziquantel (Pyrazinoisoquinoline derivative):
• The universal drug of choice for cestode (tapeworm) and trematode (fluke) infections in animals and humans (effective against Taenia, Echinococcus granulosus, Dipylidium caninum, Moniezia).
• Mechanism: Induces rapid influx of extracellular calcium across the parasite tegument, causing severe muscle contracture, vacuolization, and tegumental disruption followed by host immunological destruction.
• Piperazine is an antinematodal; Triclabendazole and Rafoxanide are fasciolicides.
• nalysis:
• (Praziquantel): Correct.

Correct option: (4) Praziquantel

• Chemical Control via Ingestion Baits:
• House flies (Musca domestica): Possess sponging/lapping mouthparts and exhibit active scavenging for carbohydrates and proteins.
• Poison baits formulated with feeding attractants (sucrose, fly sex pheromone (Z)-9-tricosene / Muscalure) and stomach insecticides (methomyl, spinosad, imidacloprid) are exceptionally effective against house flies.
• Fleas, lice, and bugs have piercing-sucking mouthparts and are strict obligate hematophages (feed exclusively on host blood); they do not consume poison baits.
• nalysis:
• (House flies): Correct.

Correct option: (4) House flies