Antidiuretic Hormone (ADH) functions as: (A) Endocrine (B)... | Agrigyan

Both statements are correct. Wilson's disease is an autosomal recessive metabolic disorder caused by mutations in the ATP7B gene encoding a copper-transporting P-type ATPase, impairing biliary copper excretion and causing toxic copper accumulation in hepatic tissue, brain basal ganglia, and cornea (Kayser-Fleischer rings).

Allopurinol is a purine analogue and suicide inhibitor of xanthine oxidase. It is metabolized by xanthine oxidase to alloxanthine (oxypurinol), which tightly binds the molybdenum active site, blocking uric acid synthesis to treat gout and hyperuricemia.

Apomorphine acts centrally on dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) to induce vomiting (A). Toxic gastric irritation stimulates peripheral vagal afferents in the stomach (C). Pyloric obstruction leads to gastric overdistension and emetic reflex (D). Allopurinol is an antigout drug and not an emetic agent.

Acute rumen indigestion (grain overload / rumen acidosis) results from rapid fermentation of readily available carbohydrates by Streptococcus bovis and Lactobacillus spp., which produce excess d-lactate and l-lactate. Because mammalian tissues lack significant d-lactate dehydrogenase to metabolize d-lactate, its systemic accumulation leads to severe d-lactic acidosis.