Q49: The genome edited GABA tomato is enriched in - Plant Genetic Engineering - Biochemistry- ICAR JRF/SRF 2024 | Agrigyan

• GABA-Enriched Genome-Edited Tomato: Developed using CRISPR-Cas9 technology by Sanatech Seed and the University of Tsukuba (Sicilian Rouge High GABA).
• Target Compound: Enriched in $\gamma$-aminobutyric acid (GABA), an inhibitory neurotransmitter in the mammalian central nervous system.
• Mechanism: Targeted deletion of the autoinhibitory domain of glutamate decarboxylase (GAD) enzyme causes sustained enzymatic hyperactivation, dramatically elevating GABA levels in mature fruit to promote cardiovascular relaxation.

Correct option: (2) Gamma amino butyric acid