Given below are two statements, one is labelled as Assertion (A)... | Agrigyan

General Agriculture Biomolecules and their Interaction Relevant to Biology Cellular Basis of Animal Physiology Cell Organization, Biomembranes, Chromatin & Acid-Base Buffers Cell Biology Blood and Circulation Chemistry of Carbohydrates and Lipids Chemistry of Amino Acids, Proteins & Nucleic Acids Fundamental Cellular Processes Respiration Enzymology Excretion Molecular Biology and Recombinant DNA Methods Digestion Bioenergetics and Intermediary Metabolism Animal Tissue Culture and Hybridoma Technology Muscle Physiology Embryo Transfer and Related Techniques Nutritional & Endocrine Biochemistry Nervous System Tissue & Organ System Biochemistry and Organ Function Tests Reproduction and Lactation Analytical & Molecular Biochemical Techniques Environmental Pollution, Detoxification & Cancer Biochemistry Molecular Immunology Climate Physiology

96

Veterinary Biochemistry- ICAR JRF/SRF 2024

Assertion & Reason

Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).

A: Allosteric enzymes are evolved to fine tune the metabolic need of the tissues R: The activity of allosteric enzymes is more sensitive to changes in substrate concentration near Km than are Michaelis— Menten enzymes with the same Vmax

In light of the above statements, choose the most appropriate answer from the options given below

Both (A) and (R) are correct and (R) is the correct explanation of (A). Both (A) and (R) are correct but (R) is NOT the correct explanation of (A) (A) is correct but (R) is not correct. (A) is not correct but (R) is correct.

General Agriculture 20
Biomolecules and their Interaction Relevant to Biology 2
Cellular Basis of Animal Physiology 3
Cell Organization, Biomembranes, Chromatin & Acid-Base Buffers 2
Cell Biology 3
Blood and Circulation 1
Chemistry of Carbohydrates and Lipids 19
Chemistry of Amino Acids, Proteins & Nucleic Acids 5
Fundamental Cellular Processes 4
Respiration 1
Enzymology 11
Excretion 2
Molecular Biology and Recombinant DNA Methods 2
Digestion 2
Bioenergetics and Intermediary Metabolism 15
Animal Tissue Culture and Hybridoma Technology 2
Muscle Physiology 1
Embryo Transfer and Related Techniques 2
Nutritional & Endocrine Biochemistry 9
Nervous System 1
Tissue & Organ System Biochemistry and Organ Function Tests 3
Reproduction and Lactation 2
Analytical & Molecular Biochemical Techniques 4
Environmental Pollution, Detoxification & Cancer Biochemistry 2
Molecular Immunology 1
Climate Physiology 1

General Agriculture

6 Topics

Agronomy, Tillage & Field Crop Production Agricultural Entomology, Nematology & Crop Protection Soil Science, Plant Nutrition & Reclamation Cell Biology, Plant Physiology & Biochemistry Agricultural Meteorology & Climate Science Crop Genetics, Plant Breeding & IPR

Biomolecules and their Interaction Relevant to Biology

2 Topics

Biophysical Principles of Biomolecular Conformation: Ramachandran Plot & Thermodynamic Stability Nucleic Acid Structures (A/B/Z-DNA, Quadruplexes) & Sequence-Specific Protein-DNA Interactions

Cell Organization, Biomembranes, Chromatin & Acid-Base Buffers

1 Topic

Fluid Mosaic Biomembrane Architecture, Transport Mechanisms & Glycocalyx

Cellular Basis of Animal Physiology

2 Topics

Cellular Ultrastructure, Nucleolus, Membrane Transport & Glycocalyx Body Fluid Compartments (ICF vs ECF), Osmolality & Starling Forces

Blood and Circulation

1 Topic

Hematopoiesis, Erythropoiesis (Liver, Spleen, Bone Marrow) & Blood Indices

Cell Biology

2 Topics

Eukaryotic Cell Cycle Regulation: Cyclins, CDKs, Checkpoints (G1/S, G2/M) & Senescence Membrane Ultrastructure, Lipid Rafts & Macromolecular Translocation across Membranes

Chemistry of Carbohydrates and Lipids

4 Topics

Monosaccharides, Oligosaccharides, Stereochemistry & Reducing Sugar Dynamics Homopolysaccharides & Heteropolysaccharides (Mucopolysaccharides/GAGs) Fatty Acid Classification, Saturated vs Unsaturated & Trans-Fatty Acids Simple, Complex & Derived Lipids: Phospholipids, Sphingolipids & Glycolipids

Chemistry of Amino Acids, Proteins & Nucleic Acids

2 Topics

Amino Acid Classification, Physicochemical Properties, Zwitterions & Isoelectric Point Peptide Bond Formation & Primary/Secondary/Tertiary/Quaternary Protein Structure

Fundamental Cellular Processes

3 Topics

DNA Repair Pathways: Base/Nucleotide Excision, Non-Homologous End Joining & Homologous Recombination Translation Mechanisms, Ribosome Subunits, Polysome Profiling & Translational Ribosomal Stalling Epigenetic Gene Regulation: DNA Methylation, Histone Code & Non-Coding RNAs (miRNA, siRNA, lncRNA)

Respiration

1 Topic

Pulmonary Gas Exchange, Partial Pressures (Venous pO2 40 mmHg) & V/Q Matching

Enzymology

4 Topics

Allosteric Regulation, Covalent Modification, Proenzymes (Zymogens) & Isoenzymes Active Enzyme Classification (EC System 1-7), Nomenclature & Coenzymes/Cofactors Enzyme Inhibition: Competitive, Non-Competitive, Uncompetitive & Irreversible Enzyme Kinetics: Michaelis-Menten Model, Lineweaver-Burk Plot, Km & Vmax

Excretion

2 Topics

Renal Functional Anatomy, Glomerular Filtration Rate (GFR) & Renal Clearance Endocrine Regulation of Renal Function: Aldosterone (Distal Tubule), ADH & ANP

Bioenergetics and Intermediary Metabolism

5 Topics

Glycolytic Pathway, Pyruvate Oxidation & Aerobic/Anaerobic Energetics Hexose Monophosphate (HMP) Shunt, Uronic Acid Pathway & Gluconeogenesis De Novo Fatty Acid Synthesis, Triacylglycerol & Phospholipid Biosynthesis Tricarboxylic Acid (TCA/Krebs) Cycle, Amphibolic Nature & Anaplerosis Glycogen Metabolism: Glycogenesis, Glycogenolysis & Reciprocal Regulation

Digestion

2 Topics

Ruminant Pre-Gastric Fermentative Digestion: Rumen Ecology, Holotrichs & VFAs Nutrient Absorption Mechanisms across Rumen, Small Intestine & Large Intestine

Molecular Biology and Recombinant DNA Methods

2 Topics

Molecular Cloning Strategies: Restriction-Modification, Linkers/Adaptors & Directional Ligation Genomic & cDNA Library Construction, Screening & Ribosome-Bound Transcriptome Probing

Animal Tissue Culture and Hybridoma Technology

2 Topics

Primary Cell Culture vs Established Cell Lines: Media Formulation, Sera & Subculturing Protocols Cellular Immunotherapies: CAR-T Cell Engineering & Therapeutic Antibody Production

Molecular Biology & Recombinant DNA Technology

4 Topics

DNA Replication in Prokaryotes & Eukaryotes: Enzymes, Okazaki Fragments & Proofreading DNA Damage, Mutations & Repair Systems (BER, NER, Mismatch, Double-Strand) Transcription Mechanisms, RNA Polymerases, Promoters & Post-Transcriptional Processing Gene Expression Regulation: Lac Operon, Trp Operon & Eukaryotic Transcription Factors

Muscle Physiology

1 Topic

Muscle Energetics, Fiber Types (Red vs White), Rigor Mortis & Muscle Fatigue

Embryo Transfer and Related Techniques

2 Topics

Somatic Cell Nuclear Transfer (SCNT), Microinjection & Animal Cloning Milestones Transgenic Animal Production: Microinjection, Retro-viral Vectors, Stem Cells & Gene Farming

Nervous System

1 Topic

Motor Control & Cerebellar Coordination: Cerebellum as Error-Correcting Device

Nutritional & Endocrine Biochemistry

4 Topics

Peptide & Steroid Hormones: Classification, Biosynthesis & Signal Transduction Fat-Soluble Vitamins (A, D, E, K): Chemistry, Biological Role & Deficiency Water-Soluble Vitamins (B-Complex, Vitamin C): Coenzymatic Roles & Deficiency Metabolic Integration in Well-Fed, Starvation, Lactation & Diabetes Mellitus

Tissue & Organ System Biochemistry and Organ Function Tests

2 Topics

Muscle, Bone & Connective Tissue Biochemistry: Mineralization & Contraction Energetics Hepatic Function Tests: Bilirubin Metabolism, Jaundice, Transaminases & Alkaline Phosphatase

Analytical & Molecular Biochemical Techniques

2 Topics

Chromatography: Gel Filtration, Ion-Exchange, Affinity, TLC & HPLC Spectroscopy (UV-Vis, Fluorescence, Circular Dichroism) & Mass Spectrometry

Reproduction and Lactation

2 Topics

Male Reproductive Physiology: Spermatogenesis, Sertoli Cells & Pheromones Female Reproductive Cyclicity: Two vs Three Wave Estrous Cycles & Ovulation

Environmental Pollution, Detoxification & Cancer Biochemistry

2 Topics

Phase I & Phase II Xenobiotic Biotransformation: Cytochrome P450 & Conjugations Reactive Oxygen Species (ROS), Free Radicals, Antioxidant Systems (SOD, Catalase, GPx)

Climate Physiology

1 Topic

Climatic Heat Stress in Domestic Livestock: Heat Tolerance Indices at 65% RH

Molecular Immunology

1 Topic

Immunoglobulin Superfamily: Isotypes, Variable Domain Genetics & Somatic Hypermutation

Veterinary Biochemistry- ICAR JRF/SRF 2024

120 Questions Bilingual

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4 Exams

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RSSB Agriculture Exams

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