Q42: What is a common application of bioinformatics in personalized medicine? - Software Engineering - Computer Application- ICAR JRF/SRF 2024 | Agrigyan

• Personalized Medicine and Bioinformatics:
• Personalized (precision) medicine tailors disease prevention and healthcare interventions to an individual's unique genetic profile and molecular phenotype.
• Genome-Wide Association Studies (GWAS) scan whole genomes across patient cohorts to discover single-nucleotide polymorphisms (SNPs) and genetic variants associated with disease susceptibility, prognosis, and pharmacogenomic drug responses.
• Bioinformatics tools interpret GWAS loci to predict patient-specific drug efficacy and adverse drug reactions (ADRs).
• Wet-lab techniques like protein crystallization, virus isolation, and mRNA isolation are physical bench methods, not computational genomics applications.
• Conclusion: Genome-wide association studies (Option 1).

Correct option: (1) Genome-wide association studies