Pharmacotherapeutic Barrier in Bacterial Meningitis: The primary therapeutic hurdle in managing bacterial meningitis in livestock is the limited penetration of antimicrobial agents across the blood-brain and blood-CSF barriers into infected neural parenchyma and meninges.
Clinical Strategy: Successful therapy requires high-dose bactericidal lipophilic antibiotics (or agents capable of crossing inflamed meninges, such as third-generation cephalosporins, trimethoprim-sulfonamides, or fluoroquinolones).
Correct option: (3) Limited penetration of antibiotics into nervous tissue
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112
Veterinary Medicine- ICAR JRF/SRF 2024
MCQ (Single Correct)
What is the primary mode of transmission for Newcastle disease virus (NDV)?
Transmission Mode of Newcastle Disease: Newcastle Disease Virus (NDV / Avian orthoavulavirus 1) is transmitted primarily via the respiratory route through the inhalation of airborne aerosol droplets and infectious dust, as well as oral ingestion of feces-contaminated feed and water.
Correct option: (4) Inhalation of airborne droplets
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113
Veterinary Medicine- ICAR JRF/SRF 2024
MCQ (Single Correct)
What was the purpose of the Glanders and Farcy Act of 18997
Legislative Intent of the 1899 Act: The Glanders and Farcy Act of 1899 was enacted in British India to control and eradicate highly contagious, fatal zoonotic diseases—specifically Glanders and Farcy (Burkholderia mallei)—affecting horses, mules, and asses.
Provisions: Empowered veterinary authorities to enforce mandatory quarantine, mallein testing, and compulsory slaughter of infected equids to protect public health and military cavalry.
Correct option: (2) To control highly contagious diseases primarily affecting equines, mules, and asses
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114
Veterinary Medicine- ICAR JRF/SRF 2024
MCQ (Single Correct)
Which type of transfusion is recommended when there is anemia with hypovolemia?
Indications for Whole Blood Transfusion: When an animal suffers from severe acute anemia complicated by hypovolemia (such as massive acute hemorrhage from trauma or abomasal ulcers), whole blood transfusion is mandatory.
Therapeutic Objective: Whole blood concurrently restores oxygen-carrying erythrocyte mass and expands intravascular oncotic and hydrostatic plasma volume, preventing cardiovascular shock.
Correct option: (3) Whole blood
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115
Veterinary Medicine- ICAR JRF/SRF 2024
MCQ (Single Correct)
Which tick species is the primary vector for the transmission of Kyasanur Forest Disease?
Primary Vector of KFD: The forest hard tick Haemaphysalis spinigera is the principal biological vector transmitting the Kyasanur Forest Disease virus (Flaviviridae) in the Western Ghats of India, with unfed nymphs actively questing on forest floor litter to bite human and animal hosts.
Correct option: (2) Haemaphysalis spinigera
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