• Assertion (A): True. Lysosomes are membrane-delimited eukaryotic organelles containing over 50 acidic hydrolases (proteases, lipases, nucleases, glycosidases) that break down macromolecules, autophagocytose damaged organelles, and recycle monomeric constituents.
• Reason (R): True. The lysosomal limiting membrane maintains an acidic lumen ($pH \sim 4.5-5.0$ driven by V-type $\text{H}^+$-ATPases), sequestering destructive lytic enzymes away from the neutral cytosol ($pH \sim 7.2$). Upon macromolecular hydrolysis, specific permeases and carrier proteins transport the resulting amino acids, monosaccharides, and nucleotides into the cytoplasm for anabolic metabolism.
• Relationship: Reason (R) provides the functional and physiological explanation for the compartmentalized digestive architecture described in Assertion (A) (Option 1).

Correct option: (1) Both (A) and (R) are true and (R) is the correct explanation of (A)